Title : Carbachol alleviates rat cytokine release and organ dysfunction induced by lipopolysaccharide.

Pub. Date : 2011 Jul

PMID : 20805763






2 Functional Relationships(s)
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1 RESULTS: Carbachol inhibited expression of TNF-alpha and IL-6 after LPS injection and had no significant effect on IL-10 in rat endotoxemia model. Carbachol tumor necrosis factor Rattus norvegicus
2 Cell experiments also showed that increases of TNF-alpha and IL-6 after LPS stimulation could be significantly inhibited by carbachol or nicotine, whereas IL-10 was not apparently altered. Carbachol tumor necrosis factor Rattus norvegicus