Title : Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription.

Pub. Date : 2010 Sep 24

PMID : 20804754






2 Functional Relationships(s)
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1 Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription. lysophosphatidic acid mitogen-activated protein kinase 3 Homo sapiens
2 Our data implicate ERK1 as an important mediator of LPA signaling leading to upregulation of SphK1 and point to SphK1 and sphingosine-1-phosphate production as potential therapeutic targets in gastric cancer. lysophosphatidic acid mitogen-activated protein kinase 3 Homo sapiens