Pub. Date : 2010 Sep 24
PMID : 20804754
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription. | lysophosphatidic acid | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | Our data implicate ERK1 as an important mediator of LPA signaling leading to upregulation of SphK1 and point to SphK1 and sphingosine-1-phosphate production as potential therapeutic targets in gastric cancer. | lysophosphatidic acid | mitogen-activated protein kinase 3 | Homo sapiens |