Title : Caspase-8 and p38MAPK in DATS-induced apoptosis of human CNE2 cells.

Pub. Date : 2010 Sep

PMID : 20802973






4 Functional Relationships(s)
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Protein Name
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1 Caspase-8 and p38MAPK in DATS-induced apoptosis of human CNE2 cells. diallyl trisulfide caspase 8 Homo sapiens
2 In this study, we investigated the function of p38 mitogen-activated protein kinase (MAPK) and caspase-8 in DATS-induced apoptosis of human CNE2 cells using MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], flow cytometry assay, and Western blotting. diallyl trisulfide caspase 8 Homo sapiens
3 The results indicated that DATS activates p38MAPK and caspase-8, but both inhibitors have an effect on P38MAPK and caspase-8 activity. diallyl trisulfide caspase 8 Homo sapiens
4 In conclusion, our data indicate that p38MAPK and caspase-8 are involved in the process of DATS-induced apoptosis in human CNE2 cells and interact with each other. diallyl trisulfide caspase 8 Homo sapiens