Pub. Date : 2010 Sep
PMID : 20802973
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Caspase-8 and p38MAPK in DATS-induced apoptosis of human CNE2 cells. | diallyl trisulfide | caspase 8 | Homo sapiens |
2 | In this study, we investigated the function of p38 mitogen-activated protein kinase (MAPK) and caspase-8 in DATS-induced apoptosis of human CNE2 cells using MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], flow cytometry assay, and Western blotting. | diallyl trisulfide | caspase 8 | Homo sapiens |
3 | The results indicated that DATS activates p38MAPK and caspase-8, but both inhibitors have an effect on P38MAPK and caspase-8 activity. | diallyl trisulfide | caspase 8 | Homo sapiens |
4 | In conclusion, our data indicate that p38MAPK and caspase-8 are involved in the process of DATS-induced apoptosis in human CNE2 cells and interact with each other. | diallyl trisulfide | caspase 8 | Homo sapiens |