Title : Effects of protocatechuic acid on trans fat induced hepatic steatosis in mice.

Pub. Date : 2010 Sep 22

PMID : 20799701






1 Functional Relationships(s)
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1 Results showed that TFA diet significantly enhanced hepatic activity and mRNA expression of fatty acid synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, stearoyl-CoA desaturase-1, and SREBP-1c (P<0.05); however, the intake of PCA significantly diminished the activity and mRNA expression of these lipogenic factors and decreased hepatic lipid accumulation (P<0.05). Trans Fatty Acids sterol regulatory element binding transcription factor 1 Mus musculus