Title : 12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases.

Pub. Date : 2010 Sep 7

PMID : 20798033






1 Functional Relationships(s)
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1 This study demonstrates that increases in cellular lipid peroxides, induced by disruption of glutathione peroxidase 4, induce cellular PTP oxidation and reduce the activity of PDGF receptor targeting PTPs. Lipid Peroxides glutathione peroxidase 4 Homo sapiens