Title : Effect of phosphamidon on convulsive behavior and biochemical parameters: modulation by progesterone and 4'-chlorodiazepam in rats.

Pub. Date : 2010 Oct

PMID : 20737266






2 Functional Relationships(s)
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1 PROG significantly increased the AChE activity in untreated rats, while PROG and 4"-CD reversed the AChE activity inhibition induced by PHOS. Progesterone acetylcholinesterase Rattus norvegicus
2 The study indicates a possible anticonvulsive mechanism of neurosteroids, since both PROG and 4"-CD reversed PHOS-induced inhibition of AChE activity. Progesterone acetylcholinesterase Rattus norvegicus