Title : Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids.

Pub. Date : 2010 Oct 22

PMID : 20732876






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CYP2C/2J isoforms converting AA to epoxyeicosatrienoic acids (EETs) preferentially epoxidized the omega-3 double bond and thereby produced 17,18-epoxyeicosatetraenoic (17,18-EEQ) and 19,20-epoxydocosapentaenoic acid (19,20-EDP) from EPA and DHA. eets cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus