Title : Redox regulation of responses to hypoxia and NO-cGMP signaling in pulmonary vascular pathophysiology.

Pub. Date : 2010 Aug

PMID : 20716294






1 Functional Relationships(s)
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1 Our studies in endothelium-rubbed bovine pulmonary arteries suggest increased glucose-6-phosphate dehydrogenase levels (compared to coronary arteries) seem to maintain a tonic peroxide-mediated relaxation removed by hypoxia through NADPH fueling superoxide generation from Nox oxidase. NADP glucose-6-phosphate dehydrogenase Bos taurus