Title : Metabolism of 1'- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7.

Pub. Date : 2010 Nov

PMID : 20713656






1 Functional Relationships(s)
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1 Consistent with these observations, the UGT1A4 inhibitor hecogenin and the UGT2B7 substrate diclofenac potently inhibited the N- and O-glucuronidation of 1"-hydroxymidazolam in HLMs, respectively. 1-hydroxymethylmidazolam UDP glucuronosyltransferase family 2 member B7 Homo sapiens