Pub. Date : 2010 Oct 29
PMID : 20708061
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Relationship between brain and plasma carbaryl levels and cholinesterase inhibition. | Carbaryl | butyrylcholinesterase | Rattus norvegicus |
| 2 | Carbaryl is a N-methylcarbamate pesticide and, like others in this class, is a reversible inhibitor of cholinesterase (ChE) enzymes. | Carbaryl | butyrylcholinesterase | Rattus norvegicus |
| 3 | Carbaryl is a N-methylcarbamate pesticide and, like others in this class, is a reversible inhibitor of cholinesterase (ChE) enzymes. | Carbaryl | butyrylcholinesterase | Rattus norvegicus |
| 4 | Although studied for many years, there is a surprising lack of information relating tissue levels of carbaryl with ChE activity in the same animals. | Carbaryl | butyrylcholinesterase | Rattus norvegicus |
| 5 | Additionally, the time-course of plasma ChE activity and carbaryl levels in adult rats was determined after a 30 mg/kg dosage of carbaryl. | Carbaryl | butyrylcholinesterase | Rattus norvegicus |
| 6 | Finally, the dose-related relationship between tissue levels of carbaryl and ChE activity was described using a first order exponential decay function with an asymptote. | Carbaryl | butyrylcholinesterase | Rattus norvegicus |
| 7 | This indicates that age-related differences in brain ChE inhibition by carbaryl are unlikely to be the result of greater tissue levels of the pesticide in PND11 animals. | Carbaryl | butyrylcholinesterase | Rattus norvegicus |
| 8 | These are the first studies to report the relationship between brain and plasma tissue levels of carbaryl and ChE activity on an individual animal basis. | Carbaryl | butyrylcholinesterase | Rattus norvegicus |