Title : (+)-Cholesten-3-one induces differentiation of neural stem cells into dopaminergic neurons through BMP signaling.

Pub. Date : 2010 Nov

PMID : 20708045






2 Functional Relationships(s)
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1 (+)-Cholesten-3-one significantly increases the expression of BMPR IB, but not BMPR IA or BMPR II; p-Smad1/5/8 positive nuclei and expression of p-Smad1/5/8 were detected in NSCs treated with (+)-Cholesten-3-one, indicating that (+)-Cholesten-3-one may activate the BMP signaling. (+)-cholesten-3-one SMAD family member 1 Homo sapiens
2 (+)-Cholesten-3-one significantly increases the expression of BMPR IB, but not BMPR IA or BMPR II; p-Smad1/5/8 positive nuclei and expression of p-Smad1/5/8 were detected in NSCs treated with (+)-Cholesten-3-one, indicating that (+)-Cholesten-3-one may activate the BMP signaling. (+)-cholesten-3-one SMAD family member 1 Homo sapiens