Title : Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate.

Pub. Date : 2010 Sep

PMID : 20700770






1 Functional Relationships(s)
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1 25HC3S reduced TNFalpha-induced inflammatory response by increasing cytoplasmic IkappaBalpha levels, decreasing NFkappaB nuclear translocation, and consequently repressing expression of NFkappaB-dependent genes, IL-1beta, TNFalpha, and TRAF1. 25-hydroxycholesterol 3-sulfate interleukin 1 beta Rattus norvegicus