Pub. Date : 2010 Sep
PMID : 20696983
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Vascular smooth muscle cell differentiation to an osteogenic phenotype involves TRPM7 modulation by magnesium. | Magnesium | transient receptor potential cation channel, subfamily M, member 7 | Mus musculus |
| 2 | TRPM 7 activation was decreased by calcification medium, an effect reversed by magnesium. | Magnesium | transient receptor potential cation channel, subfamily M, member 7 | Mus musculus |
| 3 | Magnesium negatively regulates vascular calcification and osteogenic differentiation through increased/restored TRPM7 activity and increased expression of anticalcification proteins, including osteopontin, BMP-7, and matrix Gla protein. | Magnesium | transient receptor potential cation channel, subfamily M, member 7 | Mus musculus |