Pub. Date : 2010 Sep 1
PMID : 20696580
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In particular, methoxy types of flavones and flavonols such as chrysoeriol and isorhamnetin showed strong and selective inhibition against CYP1B1. | 3-methylquercetin | cytochrome P450 family 1 subfamily B member 1 | Homo sapiens |
| 2 | The results suggested that chrysoeriol and isorhamnetin fit well into the active site of CYP1B1, but do not fit into the active site of CYP1A2 and 1A1 because of steric collisions between the methoxy substituent of these methoxyflavonoids and Ser-122 in CYP1A1 and Thr-124 in CYP1A2. | 3-methylquercetin | cytochrome P450 family 1 subfamily B member 1 | Homo sapiens |