Title : Stimulant effect of nitrite on the activation of benzo[a]pyrene-7,8-dihydrodiol in human polymorphonuclear leucocytes.

Pub. Date : 1994 Aug

PMID : 20692968






2 Functional Relationships(s)
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1 Addition of nitrite to the MPO/H(2)O(2) system markedly increased the formation of (+)-anti-BPDE. Nitrites myeloperoxidase Homo sapiens
2 Taken together, the results indicate that the principal pathway for the nitrite-stimulated formation of (+)-anti-BPDE in PMA-activated PMNs involves participation of MPO, whereas alternative pathways seem to be operative in the formation of BP-7,8-dione. Nitrites myeloperoxidase Homo sapiens