Pub. Date : 2010 Aug
PMID : 20689756
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | EPA-FFA in cell culture medium was incorporated rapidly into phospholipid membranes of HCA-7 human CRC cells and acted as a substrate for COX-2, leading to reduced synthesis of PGE(2) and generation of PGE(3). | Prostaglandins E | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | EPA-FFA in cell culture medium was incorporated rapidly into phospholipid membranes of HCA-7 human CRC cells and acted as a substrate for COX-2, leading to reduced synthesis of PGE(2) and generation of PGE(3). | Prostaglandins E | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 3 | We conclude that EPA-FFA drives a COX-2-dependent "PGE(2)-to-PGE(3) switch" in human CRC cells and that PGE(3) acts as a partial agonist at the PGE(2) EP4 receptor. | Prostaglandins E | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 4 | We conclude that EPA-FFA drives a COX-2-dependent "PGE(2)-to-PGE(3) switch" in human CRC cells and that PGE(3) acts as a partial agonist at the PGE(2) EP4 receptor. | Prostaglandins E | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 5 | We conclude that EPA-FFA drives a COX-2-dependent "PGE(2)-to-PGE(3) switch" in human CRC cells and that PGE(3) acts as a partial agonist at the PGE(2) EP4 receptor. | Prostaglandins E | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 6 | We conclude that EPA-FFA drives a COX-2-dependent "PGE(2)-to-PGE(3) switch" in human CRC cells and that PGE(3) acts as a partial agonist at the PGE(2) EP4 receptor. | Prostaglandins E | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |