Title : Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cells.

Pub. Date : 2010 Dec 8

PMID : 20688428






1 Functional Relationships(s)
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1 More importantly, HylP"s metabolic process of hyaluronan into non-detrimental oligosaccharides significantly decreased breast cancer cell proliferation, migration and invasion by disrupting Erk1/2 activation and RhoA expression. Hyaluronic Acid ras homolog family member A Homo sapiens