Title : Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus.

Pub. Date : 2010 Oct

PMID : 20686906






3 Functional Relationships(s)
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1 Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus. Harmine brain-derived neurotrophic factor Rattus norvegicus
2 Brain-derived neurotrophic factor (BDNF) hippocampal levels were assessed in imipramine and harmine-treated rats by ELISA sandwich assay. Harmine brain-derived neurotrophic factor Rattus norvegicus
3 Interestingly, chronic administration of harmine at the higher doses (10 and 15 mg/kg), but not imipramine, increased BDNF protein levels in rat hippocampus. Harmine brain-derived neurotrophic factor Rattus norvegicus