Title : Cutting edge: all-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu.

Pub. Date : 2010 Sep 1

PMID : 20679534






3 Functional Relationships(s)
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1 All-trans retinoic acid (atRA), the active derivative of vitamin A, has been demonstrated to promote Foxp3(+) Treg differentiation and suppress Th17 development. Tretinoin forkhead box P3 Mus musculus
2 All-trans retinoic acid (atRA), the active derivative of vitamin A, has been demonstrated to promote Foxp3(+) Treg differentiation and suppress Th17 development. Tretinoin forkhead box P3 Mus musculus
3 We found that nTregs treated with atRA were resistant to Th17 and other Th cell conversion and maintained Foxp3 expression and suppressive activity in the presence of IL-6 in vitro. Tretinoin forkhead box P3 Mus musculus