Title : Phenotype reversal in induced mutants of CHO cells: analysis of the reversed cell lines.

Pub. Date : 1991 Jul

PMID : 2067528






1 Functional Relationships(s)
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1 We have previously shown that descendants of CHO-derived hprt or aprt mutants induced by ethyl methanesulphonate usually undergo a rapid loss of the mutant phenotype during the 10 generations or so of culture in non-selective medium immediately following mutagenesis (Bradley, 1980; Bradley and Laviolette, 1989). Ethyl Methanesulfonate hypoxanthine-guanine phosphoribosyltransferase Cricetulus griseus