Title : Development of methotrexate proline prodrug to overcome resistance by MDA-MB-231 cells.

Pub. Date : 2010 Sep 1

PMID : 20674353






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Proline prodrug of methotrexate (Pro-MTX) was designed as a substrate of prolidase which is specific for imido bond of dipeptide containing proline and expected to penetrate MDA-MB-231 cells more efficiently. Proline peptidase D Homo sapiens
2 Proline prodrug of methotrexate (Pro-MTX) was designed as a substrate of prolidase which is specific for imido bond of dipeptide containing proline and expected to penetrate MDA-MB-231 cells more efficiently. Proline peptidase D Homo sapiens