Pub. Date : 2010 Jul 21
PMID : 20657775
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The ability of oligosaccharides to compete with HS for FGF2 and VEGF165 binding significantly increased with oligosaccharide length and sulfation. | Oligosaccharides | fibroblast growth factor 2 | Homo sapiens |
| 2 | The ability of oligosaccharides to compete with HS for FGF2 and VEGF165 binding significantly increased with oligosaccharide length and sulfation. | Oligosaccharides | fibroblast growth factor 2 | Homo sapiens |
| 3 | Correspondingly, the inhibitory potential of oligosaccharides against FGF2- and VEGF165-induced endothelial cell responses was greater in longer oligosaccharide species that were comprised of disaccharides bearing both 2-O- and N-sulfation (2SNS). | Oligosaccharides | fibroblast growth factor 2 | Homo sapiens |
| 4 | Correspondingly, the inhibitory potential of oligosaccharides against FGF2- and VEGF165-induced endothelial cell responses was greater in longer oligosaccharide species that were comprised of disaccharides bearing both 2-O- and N-sulfation (2SNS). | Oligosaccharides | fibroblast growth factor 2 | Homo sapiens |
| 5 | Inhibition of FGF2- and VEGF165-dependent endothelial tube formation strongly correlated with oligosaccharide length and sulfation with 10-mer and 12-mer 2SNS oligosaccharides being the most potent species. | Oligosaccharides | fibroblast growth factor 2 | Homo sapiens |
| 6 | Inhibition of FGF2- and VEGF165-dependent endothelial tube formation strongly correlated with oligosaccharide length and sulfation with 10-mer and 12-mer 2SNS oligosaccharides being the most potent species. | Oligosaccharides | fibroblast growth factor 2 | Homo sapiens |
| 7 | FGF2- and VEGF165-induced activation of MAPK pathway was inhibited by biologically active oligosaccharides correlating with the specific phosphorylation events in FRS2 and VEGFR-2, respectively. | Oligosaccharides | fibroblast growth factor 2 | Homo sapiens |