Title : Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients.

Pub. Date : 2010 Aug

PMID : 20653675






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 WHAT THIS STUDY ADDS * Association of functional CES1 gene number with AUC ratio [(SN-38 + SN-38G)/irinotecan], an in vivo index of CES activity, was observed in patients with irinotecan monotherapy. 7-ethyl-10-hydroxycamptothecin beta-glucuronide carboxylesterase 1 Homo sapiens