Title : COX-2 expression and effects of COX-2 inhibition in colorectal carcinomas and their liver metastases.

Pub. Date : 2010 Jun

PMID : 20651346






1 Functional Relationships(s)
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1 Following stimulation with different concentrations of the selective COX-2 inhibitor meloxicam, apoptosis was assessed immunohistochemically after 6 h and 12 h. All primary carcinomas and 56 out of the 57 liver metastases showed various degrees of cytoplasmatic COX-2 expression being with a reduction and in the liver metastases. Meloxicam mitochondrially encoded cytochrome c oxidase II Homo sapiens