Pub. Date : 1995 Oct
PMID : 20650149
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cellular neurotoxicity of trivalent manganese bound to transferrin or pyrophosphate studied in human neuroblastoma (SH-SY5Y) cell cultures. | Manganese | transferrin | Homo sapiens |
| 2 | Previous studies have shown that cellular uptake of manganese is related to its binding to transferrin. | Manganese | transferrin | Homo sapiens |
| 3 | Therefore, the cytotoxic activity of manganese bound as manganic ion to either transferrin or pyrophosphate was investigated in the cloned human neuroblastoma cell line SH-SY5Y. | Manganese | transferrin | Homo sapiens |
| 4 | These findings suggest that transferrin not only mediates manganese transport into the neurone, but also protects the cell from damage caused by the manganic ion. | Manganese | transferrin | Homo sapiens |