Title : Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin.

Pub. Date : 2010 Aug

PMID : 20649590






3 Functional Relationships(s)
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Protein Name
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1 BACKGROUND AND PURPOSE: Carboxylesterases (CEs) metabolize a wide range of xenobiotic substrates including heroin, cocaine, meperidine and the anticancer agent CPT-11. Cocaine carboxylesterase 1 Homo sapiens
2 These results correlated well with computer-assisted molecular modelling studies that suggested that hydrolysis of cocaine by hCE1 (CES1), would be unlikely to occur. Cocaine carboxylesterase 1 Homo sapiens
3 These results correlated well with computer-assisted molecular modelling studies that suggested that hydrolysis of cocaine by hCE1 (CES1), would be unlikely to occur. Cocaine carboxylesterase 1 Homo sapiens