Title : [Induction of cell cycle arrest in bladder cancer RT4 cells by capsaicin].

Pub. Date : 2010 May 11

PMID : 20646592






3 Functional Relationships(s)
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1 And the expressions of cell cycle protein P53, P21, CDK2 were detected by Western blot after the treatment of capsaicin. Capsaicin H3 histone pseudogene 16 Homo sapiens
2 After a 48-hour treatment with capsaicin, the expressions of P53 and P21 were up-regulated in contrary to the expression of CDK2. Capsaicin H3 histone pseudogene 16 Homo sapiens
3 CONCLUSION: Capsaicin induces the cell cycle arrest of bladder cancer RT4 cells G(0)/G(1) phase and growth inhibition via TRPV1 receptor by modulating the expression of P53, P21 and CDK2. Capsaicin H3 histone pseudogene 16 Homo sapiens