Pub. Date : 2010 Oct 13
PMID : 20643195
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to use c-fos like immunohistochemistry (Fos-LI) to map the trigeminal brainstem complex after intravitreal microinjection or ocular surface application of capsaicin, a selective transient receptor potential vanilloid 1 (TRPV1) agonist in male rats under barbiturate anesthesia. | Capsaicin | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | The aim of this study was to use c-fos like immunohistochemistry (Fos-LI) to map the trigeminal brainstem complex after intravitreal microinjection or ocular surface application of capsaicin, a selective transient receptor potential vanilloid 1 (TRPV1) agonist in male rats under barbiturate anesthesia. | Capsaicin | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 3 | In non-inflamed controls, intravitreal capsaicin produced peaks of Fos-LI at the trigeminal subnucleus interpolaris/caudalis (Vi/Vcvl) transition and in superficial laminae at the caudalis/upper cervical cord (Vc/C1) junction regions. | Capsaicin | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 4 | At the Vc/C1 junction intravitreal capsaicin induced Fos-LI in a dose-dependent manner, while at the Vi/Vcvl transition responses were similar after vehicle or capsaicin injections. | Capsaicin | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 5 | Two days, but not 7 days, after UV irradiation intravitreal and ocular surface capsaicin-evoked Fos-LI at the Vc/C1 junction and nucleus tractus solitarius (NTS) were markedly enhanced, whereas the responses at the Vi/Vcvl transition were not different from non-inflamed controls. | Capsaicin | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |