Title : (-)-3-(4-Chlorophenyl)-N'-[(4-[11C]cyanophenyl)sulfonyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine

Pub. Date : 2004

PMID : 20641388






2 Functional Relationships(s)
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Protein Name
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1 (-)-3-(4-chlorophenyl)-N"-[(4-[(11)C]cyanophenyl)sulfonyl]-4-phenyl- 4,5-dihydro-1H-pyrazole-1-carboxamidine ([(11)C]CB1-(-)-12a) is a potent and selective CB1 antagonist with nanomolar affinity and lower lipophilicity than SR141716A (9). Rimonabant cannabinoid receptor 1 Homo sapiens
2 (-)-3-(4-chlorophenyl)-N"-[(4-[(11)C]cyanophenyl)sulfonyl]-4-phenyl- 4,5-dihydro-1H-pyrazole-1-carboxamidine ([(11)C]CB1-(-)-12a) is a potent and selective CB1 antagonist with nanomolar affinity and lower lipophilicity than SR141716A (9). Rimonabant cannabinoid receptor 1 Homo sapiens