Title : 131I-Labeled recombinant anti-glycoprotein A33 antibody single chain variable fragment fused to cytosine deaminase

Pub. Date : 2004

PMID : 20641233






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The CDy part of the recombinant fusion protein deaminates 5-fluorocytosine (5-FC), the prodrug, to produce cytotoxic 5-fluorouracil after the A33scFv part binds to the A33 antigen on the cell surface. Flucytosine chromodomain Y-linked 1B Homo sapiens
2 The CDy part of the recombinant fusion protein deaminates 5-fluorocytosine (5-FC), the prodrug, to produce cytotoxic 5-fluorouracil after the A33scFv part binds to the A33 antigen on the cell surface. Flucytosine chromodomain Y-linked 1B Homo sapiens