Title : Cryptotanshinone sensitizes DU145 prostate cancer cells to Fas(APO1/CD95)-mediated apoptosis through Bcl-2 and MAPK regulation.

Pub. Date : 2010 Dec 1

PMID : 20638780






1 Functional Relationships(s)
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1 We further show that JNK and p38 MAPK act upstream of Bcl-2 expression in Fas-treated DU145 cells, and that cryptotanshinone significantly blocked activation of these kinases. ammonium ferrous sulfate mitogen-activated protein kinase 8 Homo sapiens