Title : Mesangial cells stimulated by immunoglobin A1 from IgA nephropathy upregulates transforming growth factor-beta1 synthesis in podocytes via renin-angiotensin system activation.

Pub. Date : 2010 May

PMID : 20637368






1 Functional Relationships(s)
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1 Enalaprilat and valsartan partly lowered overproduction of TGF-beta1 mRNA and excreted protein of podocytes, whereas enalaprilat plus valsartan completely restored them to the level as control. Enalaprilat transforming growth factor beta 1 Homo sapiens