Title : The Analgesic Activity of Bestatin as a Potent APN Inhibitor.

Pub. Date : 2010

PMID : 20631848






1 Functional Relationships(s)
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1 Based on the knowledge that APN can cleave several bioactive neuropeptides such as Met-enkaphalins, Leu-enkaphalins, beta-Endorphin, and so on, the anti-aminopeptidase action of Bestatin also allows it to protect endopeptides against their catabolism, exhibiting analgesic activity. ubenimex proopiomelanocortin Homo sapiens