Title : Supramolecular insulin assembly II for a sustained treatment of type 1 diabetes mellitus.

Pub. Date : 2010 Jul 27

PMID : 20628017






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Administration of a single dose of the insulin oligomer, defined here as the supramolecular insulin assembly II (SIA-II), to experimental animals rendered diabetic by streptozotocin or alloxan, released the hormone capable of maintaining physiologic glucose levels for >120 days for bovine and >140 days for recombinant human insulin without fasting hypoglycemia. Streptozocin insulin Bos taurus
2 Administration of a single dose of the insulin oligomer, defined here as the supramolecular insulin assembly II (SIA-II), to experimental animals rendered diabetic by streptozotocin or alloxan, released the hormone capable of maintaining physiologic glucose levels for >120 days for bovine and >140 days for recombinant human insulin without fasting hypoglycemia. Streptozocin insulin Bos taurus