Pub. Date : 1991 May
PMID : 2061847
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The role of chloride and bicarbonate in the control of intracellular pH (pHi) was assessed in segments of rat mesenteric resistance arteries (internal diameter about 200 microns) by measurements of chloride efflux with 36Cl-, of pHi with the pH-sensitive dye 2",7"-bis-(2-carboxyethyl)-5 (and-6)-carboxyfluorescein (BCECF) and of membrane potential with intracellular electrodes. | Bicarbonates | glucose-6-phosphate isomerase | Rattus norvegicus |
| 2 | By contrast, in the presence of bicarbonate, omission of chloride caused an increase in pHi but no change in 36Cl- efflux. | Bicarbonates | glucose-6-phosphate isomerase | Rattus norvegicus |
| 3 | Furthermore, the anion transport inhibitor 4,4"-diisothiocyanatostilbene-2,2"-disulphonic acid (DIDS) inhibited the increase in pHi seen in the presence of bicarbonate and reduced the 36Cl- efflux in the presence of bicarbonate. | Bicarbonates | glucose-6-phosphate isomerase | Rattus norvegicus |
| 4 | Furthermore, the anion transport inhibitor 4,4"-diisothiocyanatostilbene-2,2"-disulphonic acid (DIDS) inhibited the increase in pHi seen in the presence of bicarbonate and reduced the 36Cl- efflux in the presence of bicarbonate. | Bicarbonates | glucose-6-phosphate isomerase | Rattus norvegicus |