Title : Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats.

Pub. Date : 2010 Jun 30

PMID : 20614021






1 Functional Relationships(s)
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1 Valproate, a widely used antiepileptic drug, has a number of targets including GABA transaminase, voltage-gated sodium channels, glycogen synthase kinase (GSK)-3, and histone deacetylases (HDACs), and therefore may attenuate a number of TBI-associated pathologies. Valproic Acid 4-aminobutyrate aminotransferase Rattus norvegicus