Title : The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice.

Pub. Date : 2010 Aug

PMID : 20613640






2 Functional Relationships(s)
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Protein Name
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1 The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice. avasimibe amyloid beta (A4) precursor protein Mus musculus
2 Collectively, these data suggest that CI-1011 treatment reduces amyloid burden in human APP mice by limiting generation and increasing clearance of diffusible Abeta. avasimibe amyloid beta (A4) precursor protein Mus musculus