Title : The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells.

Pub. Date : 2011 Dec

PMID : 20607588






1 Functional Relationships(s)
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1 Moreover, pretreatment of HCT116 cells with the iron chelator deferoxamine mesylate salt (DFO) abrogated induction of GRP78 and GADD153 upon DHA treatment, indicating iron is required for DHA-induced ER stress. Deferoxamine mesylate DNA damage inducible transcript 3 Homo sapiens