Pub. Date : 2010 Jun
PMID : 20606811
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The cytochrome P(450) isoform (CYP2E1) specifically involved in ethanol oxidation is discussed. | Ethanol | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | The formation of carbon-centered (1-hydroxyethyl) and oxygen-centered (hydroxyl) radicals during the metabolism of ethanol is considered: the generation of hydroxyethyl radicals, which occurs likely during the process of univalent reduction of dioxygen, is highlighted and is carried out by ferric cytochrome P(450) oxy-complex (P(450)-Fe(3+)O(2) (.-)) formed during the reduction of heme-oxygen. | Ethanol | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |