Pub. Date : 1991 Jun 17
PMID : 2060617
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of glutathione S-transferase gene expression by phenobarbital in cultured adult rat hepatocytes. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 2 | Previous studies, by using Northern blotting analyses, showed that phenobarbital (PB) affects the steady-state mRNA levels of glutathione S-transferase (GST) subunits 1/2, 3/4 and 7 in both conventional cultures of adult rat hepatocytes and co-cultures, with rat liver epithelial cells [Vandenberghe et al., 1989, FEBS Lett. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 3 | Previous studies, by using Northern blotting analyses, showed that phenobarbital (PB) affects the steady-state mRNA levels of glutathione S-transferase (GST) subunits 1/2, 3/4 and 7 in both conventional cultures of adult rat hepatocytes and co-cultures, with rat liver epithelial cells [Vandenberghe et al., 1989, FEBS Lett. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 4 | Previous studies, by using Northern blotting analyses, showed that phenobarbital (PB) affects the steady-state mRNA levels of glutathione S-transferase (GST) subunits 1/2, 3/4 and 7 in both conventional cultures of adult rat hepatocytes and co-cultures, with rat liver epithelial cells [Vandenberghe et al., 1989, FEBS Lett. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 5 | Previous studies, by using Northern blotting analyses, showed that phenobarbital (PB) affects the steady-state mRNA levels of glutathione S-transferase (GST) subunits 1/2, 3/4 and 7 in both conventional cultures of adult rat hepatocytes and co-cultures, with rat liver epithelial cells [Vandenberghe et al., 1989, FEBS Lett. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 6 | Data from this study demonstrate that the increase in steady-state mRNA levels observed in both conventional culture and co-culture after 4 days PB exposure results from an increased transcriptional activity of the GST genes. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |