Pub. Date : 2010 Oct
PMID : 20606004
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Micafungin uptake into hepatocytes was inhibited by taurocholate (K(i) = 61 muM), Na(+) depletion (45-55% reduced), and 10 muM rifampin (20-25% reduced); these observations support the involvement of Na(+)-taurocholate-cotransporting polypeptide (NTCP/Ntcp) and, to a lesser extent, organic anion-transporting polypeptides in the hepatic uptake of micafungin. | Taurocholic Acid | latexin | Homo sapiens |
| 2 | In vitro biliary excretion of micafungin was reduced by 80 and 75% in the presence of the bile salt export pump (BSEP) inhibitors taurocholate (100 muM) and nefazodone (25 muM), respectively. | Taurocholic Acid | latexin | Homo sapiens |