Title : In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats.

Pub. Date : 2010 Oct

PMID : 20606004






2 Functional Relationships(s)
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1 In vitro biliary excretion of micafungin was reduced by 80 and 75% in the presence of the bile salt export pump (BSEP) inhibitors taurocholate (100 muM) and nefazodone (25 muM), respectively. Taurocholic Acid ATP binding cassette subfamily B member 11 Homo sapiens
2 In vitro biliary excretion of micafungin was reduced by 80 and 75% in the presence of the bile salt export pump (BSEP) inhibitors taurocholate (100 muM) and nefazodone (25 muM), respectively. Taurocholic Acid ATP binding cassette subfamily B member 11 Homo sapiens