Pub. Date : 1991
PMID : 2060081
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These routes include the classic reduced folate carrier and a membrane-associated folate-binding protein (mFBP). | Folic Acid | far upstream element (FUSE) binding protein 1 | Mus musculus |
| 2 | The role of an mFBP in the uptake of DDATHF was suggested from observations that (a) the mFBP showed a very high binding affinity for DDATHF, (b) murine and human leukemia cells expressing an mFBP were highly sensitive to growth inhibition by DDATHF, and (c) protection against this growth inhibition could be achieved using folic acid rather than reduced folate compounds. | Folic Acid | far upstream element (FUSE) binding protein 1 | Mus musculus |
| 3 | The role of an mFBP in the uptake of DDATHF was suggested from observations that (a) the mFBP showed a very high binding affinity for DDATHF, (b) murine and human leukemia cells expressing an mFBP were highly sensitive to growth inhibition by DDATHF, and (c) protection against this growth inhibition could be achieved using folic acid rather than reduced folate compounds. | Folic Acid | far upstream element (FUSE) binding protein 1 | Mus musculus |
| 4 | The role of an mFBP in the uptake of DDATHF was suggested from observations that (a) the mFBP showed a very high binding affinity for DDATHF, (b) murine and human leukemia cells expressing an mFBP were highly sensitive to growth inhibition by DDATHF, and (c) protection against this growth inhibition could be achieved using folic acid rather than reduced folate compounds. | Folic Acid | far upstream element (FUSE) binding protein 1 | Mus musculus |
| 5 | The role of an mFBP in the uptake of DDATHF was suggested from observations that (a) the mFBP showed a very high binding affinity for DDATHF, (b) murine and human leukemia cells expressing an mFBP were highly sensitive to growth inhibition by DDATHF, and (c) protection against this growth inhibition could be achieved using folic acid rather than reduced folate compounds. | Folic Acid | far upstream element (FUSE) binding protein 1 | Mus musculus |
| 6 | The role of an mFBP in the uptake of DDATHF was suggested from observations that (a) the mFBP showed a very high binding affinity for DDATHF, (b) murine and human leukemia cells expressing an mFBP were highly sensitive to growth inhibition by DDATHF, and (c) protection against this growth inhibition could be achieved using folic acid rather than reduced folate compounds. | Folic Acid | far upstream element (FUSE) binding protein 1 | Mus musculus |
| 7 | The role of an mFBP in the uptake of DDATHF was suggested from observations that (a) the mFBP showed a very high binding affinity for DDATHF, (b) murine and human leukemia cells expressing an mFBP were highly sensitive to growth inhibition by DDATHF, and (c) protection against this growth inhibition could be achieved using folic acid rather than reduced folate compounds. | Folic Acid | far upstream element (FUSE) binding protein 1 | Mus musculus |