Title : Multiple protein kinase pathways mediate amplified IL-6 release by human lung fibroblasts co-exposed to nickel and TLR-2 agonist, MALP-2.

Pub. Date : 2010 Sep 1

PMID : 20600219






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The protein kinase inhibitors had minimal or no effects on Ni/MALP-2-induced accumulation of HIF-1alpha protein, however, COX-2 expression and, more markedly PGE(2) production, were suppressed by LY294002, SB203580, and U0126. SB 203580 mitochondrially encoded cytochrome c oxidase II Homo sapiens