Title : Differences in the expression of endogenous efflux transporters in MDR1-transfected versus wildtype cell lines affect P-glycoprotein mediated drug transport.

Pub. Date : 2010 Jul

PMID : 20590635






1 Functional Relationships(s)
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1 As a consequence, transport of vinblastine by human Pgp in efflux experiments was markedly underestimated when transport in MDR1-transfected MDCK cells was corrected for transport obtained in wildtype cells. Vinblastine ATP binding cassette subfamily B member 1 Homo sapiens