Title : Effects of the CYP3A5*3 variant on cyclosporine exposure and acute rejection rate in renal transplant patients: a meta-analysis.

Pub. Date : 2010 Sep

PMID : 20588203






2 Functional Relationships(s)
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1 Effects of the CYP3A5*3 variant on cyclosporine exposure and acute rejection rate in renal transplant patients: a meta-analysis. Cyclosporine cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 BACKGROUND: Whether the loss-of-function allele CYP3A5*3 variant is associated with significantly impaired metabolism of cyclosporine A (CsA) in transplant patients is still controversial because of the lack of prospective, large-scale clinical studies performed among diversely ethnic populations. Cyclosporine cytochrome P450 family 3 subfamily A member 5 Homo sapiens