Title : Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8.

Pub. Date : 2010 Aug 27

PMID : 20587417






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The chimera M2-M8P (i.e. TRPM2 with the pore of TRPM8) responded to ADP-ribose and hydrogen peroxide and was regulated by extracellular and intracellular Ca(2+) as was wild-type TRPM2. Adenosine Diphosphate Ribose transient receptor potential cation channel subfamily M member 8 Homo sapiens
2 The transfer of the NUDT9 domain to the C terminus of TRPM8 produced a channel sensitive to cold, menthol, or icilin but insensitive to ADP-ribose or hydrogen peroxide. Adenosine Diphosphate Ribose transient receptor potential cation channel subfamily M member 8 Homo sapiens