Title : A multi-endpoint evaluation of cytochrome P450 1A2, 2B6 and 3A4 induction response in human hepatocyte cultures after treatment with β-naphthoflavone, phenobarbital and rifampicin.

Pub. Date : 2010 Dec

PMID : 20583967






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The concentration-dependent response and time-course for the induction of CYP1A2, CYP2B6 and CYP3A4 by inducing agents beta-naphthoflavone, phenobarbital and rifampicin, respectively were examined in two or more donors using multiple end-points (mRNA, enzyme activity and Western blot analysis). Phenobarbital cytochrome P450 family 3 subfamily A member 4 Homo sapiens