Title : Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: the STRIDE-PD study.

Pub. Date : 2010 Jul

PMID : 20582993






1 Functional Relationships(s)
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1 It has been hypothesized that providing more continuous delivery of L-dopa to the brain would reduce the risk of motor complications, and that this might be accomplished by combining L-dopa with entacapone, an inhibitor of catechol-O-methyltransferase, to extend its elimination half-life. entacapone catechol-O-methyltransferase Homo sapiens