Title : Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug-induced liver injury.

Pub. Date : 2010 Jul

PMID : 20578157






2 Functional Relationships(s)
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Protein Name
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1 The presence of two or more combined risk alleles (SOD2 Ala and GPX1 Leu) was more frequent in DILI patients (OR = 2.1; 95%CI = 1.4-3.0; Pc = 0.0006). Leucine glutathione peroxidase 1 Homo sapiens
2 CONCLUSION: Patients homozygous for the SOD2 Ala allele and the GPX1 Leu allele are at higher risk of developing cholestatic DILI. Leucine glutathione peroxidase 1 Homo sapiens